Hericium

25 mins read

In spite of its monochrome colouring, Hericium erinaceus is by any requirements among our most striking of woodland fungis. The fruitbodies appear on harmed or dropped trees generally in old (mainly deciduous) woodland.

Sadly, Hericium erinaceus (in some guidebook it is listed as Hericium erinaceum) which is commonly referred to as Bearded Tooth or Tree Hedgehog fungus, is uncommon in the UK, where it grows primarily on Beech and oak trees, and is a Biodiversity Action Strategy (BAP) types.

Circulation

A really rare sight in Britain, where it is discovered primarily in southern England and eastern Wales, Hericium erinaceus occurs likewise in many parts of Europe, being particularly extensive and plentiful in central and southern France. This types is likewise found in North America; I have actually seen woodlands in South Carolina embellished with Lion’s Manes like luxurious Christmas-tree decors (and yes, it was during the last week of December!).

Taxonomic history

When French botanist-mycologist Jean Baptiste Francois (Pierre) Bulliard described Bearded Tooth fungus in 1780 he gave it the binomial taxonomic name Hydnum erinaceus. It was Christiaan Hendrik Persoon who in 1797 moved this species to its present genus, whereupon its taxonomic name became Hericium erinaceus, which still stands today.

Etymology

Hericium, the generic name, suggests referring to a hedgehog, and is a recommendation to the spiny fertile surfaces of fungis within this grouping. As so often with the type species of a genus, the specific epithet erinaceus indicates much the same as the generic name: like a hedgehog. Picture an upturned, pallid hedgehog … It’s a pretty precise description, I ‘d state.

Recognition guide

Fruitbody

Hericium erinaceus (likewise described as the Pom-Pom mushroom) often has a roundish fruitbody with spinal columns all emerging from the very same point and cascading down like a mop head. White or pale yellow-brown turning darker with age, the fruitbody is connected to the substrate by a really short, broad stipe. These are yearly fruitbodies but they can recur in the very same put on a tree for several years. The entire fruitbody can be as big regarding 30cm throughout, although 15 to 20cm is more normal.

Spines of Hericium erinaceus have actually pointed tips and range from 1 to 5cm long.

Spores

Broadly ellipsoidal to subglobose, smooth or with a very a little roughed up surface, 5-6 x 4-5.5 µm; amyloid.

Spore print

White.

Odour/taste

Smell not unique; when cooked the taste is reportedly tasty and, to some a minimum of, rather like lobster prepared in butter.

Habitat

Saprobic, nearly constantly on beech and oak trees, stumps and fallen logs in Britain, but sometimes on other woods. Bearded Tooth fungus is also reported to fruit sometimes on piles of sawdust.

Season

July to November in Britain and Ireland. (1 ).

How does it work?

Hericium erinaceus may enhance the development and function of nerves. It might also safeguard nerves from ending up being harmed. This might assist avoid conditions such as Alzheimer’s illness or Parkinson’s disease. Hericium erinaceus likewise seems to help safeguard the mucous membrane layer of the stomach. This might assist enhance signs associated with long-lasting swelling of the stomach lining (chronic atrophic gastritis) or stomach ulcers. (2 ).

Utilizes checked in practice:

  • Policy of gastric and intestinal issues, especially in gastrointestinal swelling + Reishi, Shiitake, Coprinus
  • Avoidance of cancer disorders, particularly cancer of the stomach, intestinal tracts, esophagus and skin – according to the tumour type
  • Enhancing of the body immune system + any medical mushroom
  • Complementary therapy for neural diseases + Reishi, Cordyceps
  • Alleviating depressive moods + Cordyceps
  • Uneasyness and sleep conditions + Reishi

Other intentions for using Hericium:

Stomach problems, gastritis, soothes mucous membranes, Helicobacter pylori, celiac illness + Reishi, neurasthenia, tension, affects the NGF factor in neurodegenerative diseases (dementia, Parkinson’s disease, Alzheimer’s illness, several sclerosis), improves working of the nervous system, neuropathy, enhances concentration, increases bowel peristalsis (ideally a preparation from dried Hericium extract), multiresistant gold staphylococcus, tumour diseases (of the stomach, esophagus, large intestinal tract, liver, uterine neck), stress, uneasyness.

TCM characteristics:

  • Temperature level– neutral
  • Taste– sweet, dull
  • Tropism– spleen, stomach, heart (according to other sources + liver, kidneys or all circuits)

Impacts according to conventional Chinese medicine:

  • Strengthens the stomach and regulates its Qi
  • Replenishes the spleen and promotes digestion
  • Calms the spirit Shen and strengthens brain activity
  • Affects all organ systems (3 )

The Health Benefits of Lion’s Mane

Advocates claim that lion’s mane can aid with a range of illness, consisting of:.

  • Alzheimer’s illness
  • Stress and anxiety
  • Depression
  • High cholesterol
  • Inflammation
  • Parkinson’s disease
  • Ulcers

In addition, lion’s mane is said to strengthen the body immune system, stimulate digestion, and secure versus cancer.

So far, research study on the particular health effects of lion’s hair is fairly restricted. However, findings from animal-based research study, test-tube studies, and small scientific trials show that lion’s mane may use particular health benefits, including assistance for neuronal health. Here’s a take a look at some key study findings.

Brain Function

Lion’s hair might benefit older grownups with mild cognitive problems, according to a little research study released in Phytotherapy Research study in 2009. For the research study, researchers assigned 30 older adults with moderate cognitive impairment to take either lion’s mane extract or a placebo every day for 16 weeks. In cognitive tests offered at weeks eight, 12, and 16 of the research study, members of the lion’s hair group showed significantly higher improvements compared to members of the placebo group.

In a more current study (published in Biomedical Research study in 2011), scientists took a look at the effects of lion’s mane on brain function in mice. Outcomes revealed that lion’s mane helped protect versus memory problems triggered by the buildup of amyloid beta (a compound that forms the brain plaques connected with Alzheimer’s disease). Research studies have actually likewise shown a possible neuro-protective result against ischemic stroke.

The National Center for Complementary and Integrative Health (NCCIH) warns that while some small preliminary studies on the effect of natural supplements on cognitive function have revealed modest impacts, “direct proof is doing not have.” Claims made to the contrary are not supported by proof.

Depression

Lion’s hair might help relieve depression and stress and anxiety, suggests a small research study published in Biomedical Research in 2010. For the study, 30 menopausal females taken in cookies including either lion’s mane or a placebo every day for 4 weeks. Examining study findings, scientists observed that members of the lion’s hair group were less irritable and distressed and had less trouble focusing than members of the placebo group.

Cancer

Preliminary research suggests that lion’s hair reveals pledge in protection against cancer. For example, in a 2011 study published in Food & & Function, tests on human cells revealed that lion’s hair might assist knock out leukemia cells.

In addition, a 2011 study released in the Journal of Agricultural and Food Chemistry discovered that lion’s mane extract helped in reducing the size of cancerous colon growths in mice.9 The research study’s findings suggest that lion’s hair might assist combat colon cancer, in part by increasing activity in certain cells associated with the immune response. Another research study found that the extract might help in reducing the spread of colon cancer cells to the lungs. However, it’s prematurely to tell whether lion’s hair can assist prevent or lower cancer in humans. (4 ).

May Have Anti-Diabetic Residences

Some research study suggests that lion’s hair extracts may be beneficial for those who are attempting to handle diabetes. However once again, research studies in human beings are lacking.

A study released in 2013 discovered that lion’s mane extract not just reduced glucose levels but likewise increased insulin levels in diabetic rats when they were administered the extract for 28 days. The rats likewise showed increased high-density lipoprotein cholesterol and reduced total cholesterol, low-density lipoprotein cholesterol, and triglycerides.

There is some limited evidence that lion’s hair extract may help in reducing discomfort signs related to diabetic neuropathy. This study was done in rats, so more proof is needed, however researchers believe that the reduction in pain level of sensitivity may be due to antioxidant activity in lion’s hair. (5 ).

Stress and anxiety relief

Another 2018 research study in mice found that lion’s hair mushroom promoted the production of brand-new brain cells in the hippocampus after just 4 weeks of once-a-day treatment, which might be behind its anxiolytic (anti-anxiety) effects.

Improved cognitive function

Lion’s mane is often sold as nootropics– a cognitive-enhancing supplement.

One 2017 study in mice discovered that day-to-day supplementation of lion’s mane mushroom avoided the decline of two functions typically related to Alzheimer’s: loss of spatial short-term memory and reduced acknowledgment memory.

During the experiment, these very same mice began looking for brand-new stimuli, which engages brand-new neural paths and delays the onset of cognitive impairment.

A 2020 study likewise reported that individuals who supplemented 3 grams of lion’s hair 2 times a day (for a total of 6 grams) reported enhanced memory.

Antioxidants

Antioxidants assist your body eliminate “totally free radicals,” or molecules that can harm cells.

Research has actually shown that lion’s mane is abundant in several anti-oxidants, especially phenol, an antioxidant absorbed in the gut to lower inflammation.

In an older study in 2011, lion’s mane was put in the “reasonably high” category on their antioxidant index, along with Reishi and split gill mushrooms.

A 2021 study discovered that antioxidant activity remained steady in mushroom extracts for at least a month, decreasing by half around the 4-month mark.

Boosted resistance

With all the anti-oxidants, it’s no surprise that lion’s mane may help support your body immune system. However researchers have actually found another path to better immunity: the gut.

A 2017 study in mice discovered that the protein in lion’s mane mushrooms might improve the immune system by supporting the nest of healthy bacteria in the gut, just like prebiotics and probiotics. (6 ).

Adenoid Cystic Carcinoma/Cancer Patients going through Paclitaxel treatment?

Adenoid Cystic Carcinoma is identified and driven by particular hereditary anomalies like NFIB and MYB causing biochemical path modifications in Focal Adhesion, PI3K-AKT-MTOR Signaling, Notch Signaling and Cholesterol Metabolic Process. A cancer treatment like Paclitaxel works through a specific path mechanism of action. The objective is to have an excellent overlap between the treatment and cancer driving paths for a personalized approach which is effective. In such a condition any food or dietary supplement which has a contrary result to the treatment or minimizes the overlap ought to be prevented. As an example, Lion’s Mane Mushroom need to be prevented for Adenoid Cystic Cancer together with treatment Paclitaxel. Lion’s Mane Mushroom impacts pathways/processes like Focal Adhesion which either promote motorists of the disease and/or nullify the treatment impact. Some of the aspects which ought to be thought about when choosing nutrition are type of cancer, treatments and supplements being taken presently (if any), age, gender, BMI, lifestyle and any hereditary anomaly details (if available).

Angiosarcoma Cancer Patients going through Vincristine Treatment?

Angiosarcoma is defined and driven by specific genetic mutations like TP53 and MAP3K9 resulting in biochemical path modifications in Epithelial to Mesenchymal Transition, Adherens junction, NFKB Signaling, PI3K-AKT-MTOR Signaling and MAPK Signaling. A cancer treatment like Vincristine works through specific path mechanisms. The goal is to have an excellent overlap between the treatment and cancer driving paths for a customized technique. In such a condition any food or nutritional supplement which has a suitable impact to the treatment or lowers the overlap ought to be considered. As an example, Lion’s Mane Mushroom ought to be thought about for Angiosarcoma along with treatment Vincristine. Lion’s Hair Mushroom affects pathways/processes like Epithelial to Mesenchymal Transition and Adherens junction which either block motorists of the disease (Angiosarcoma) and/or improve the treatment result.

For Healthy Individuals with CDC73 Anomaly Associated Genetic Danger?

Various business offer panels of genes to be checked for evaluating genetic risk to various cancers. These panels cover genes related to cancers of the breast, ovary, uterus, prostate, and gastrointestinal system and others. Genetic screening of these genes may confirm a medical diagnosis and help guide treatment and management decisions. Identification of a disease-causing variant might likewise assist screening and medical diagnosis of at-risk loved ones. CDC73 is among the genes usually readily available in panels for cancer risk screening.

CDC73 mutation causes biochemical pathways WNT Beta-catenin Signaling, Stem Cell Signaling and Angiogenesis to get affected. These pathways are direct or indirect motorists of cancer molecular endpoints. Lion’s Mane Mushroom need to be prevented when the hereditary panel recognizes mutation of CDC73 for Neuroendocrine Cancer. Lion’s Mane Mushroom effects pathways like WNT Betacatenin Signaling and Stem Cell Signaling and develops unfavorable impacts with CDC73 and related conditions.

For Healthy Individuals with TP53 Mutation Associated Genetic Threat?

TP53 is one of the genes readily available in panels for cancer danger screening. TP53 mutation triggers biochemical paths P53 Signaling, MAPK Signaling, Stem Cell Signaling, Estrogen Signaling and Autophagy to get affected. These paths are direct or indirect drivers of cancer molecular endpoints. Consider taking Lion’s Mane Mushroom supplements when the hereditary panel identifies mutation in TP53 for Breast Cancer and Lung Cancer. Lion’s Mane Mushroom effects pathways like P53 Signaling and MAPK Signaling and develops an encouraging impact in those with TP53 anomaly and related conditions.

How to Pick, Store, and Consume Lion’s Hair Mushrooms

If you have actually often visited a farmers’ market recently (or live near a bougie supermarket), you might have seen them. They look like pale little tribbles– fluffy and soft and type of cute– but they are mushrooms, and they have an ominous side (they murder trees).

Lion’s hair mushrooms get their ferocious name from their appearance, but they have a moderate, kind of sweet flavor that some have actually compared to crab or even marzipan. I can find both almonds and a minor air of seafood at the front, but those subtle flavors rapidly pave the way to moderate, earthy mushroomy-ness. They’re excellent on their own, and they’re spongey little bodies take in whatever flavorful fat you prepare them in. They’re enjoyable to take a look at, fun to prep– you can rip ’em apart like soft bread– and fun to consume. But, like all mushrooms, they need a little specialized care.

How to pick ’em

Lion’s mane mushrooms are parasites that assault and eliminate living trees so that they may feast upon their dead bodies. Foraging for them is for that reason an act of service. In addition to upright trees, the fluffy threats can be found on stumps, fallen branches, or dead, fallen trees (their favorite food). Watch out if you reside in an area that has a great deal of birch, maple, or oak– specifically if that birch, maple, or oak has fallen over.

You can likewise find them at expensive grocery stores for fancy individuals (or at farmer’s markets). They ought to look fluffy, and either white or pale yellow (they will darken as they age), and must be dry and free from bruises (dirt is okay). They should not have much of a smell, so prevent specimens that smell like anything other than mushrooms.

How to save ’em

Lion’s hair mushrooms will last approximately a week if appropriately kept and cared for, and they really aren’t that picky. Just keep them away from water– do not wash them up until you are ready to eat them, if at all– and keep them in your refrigerator far from the direct flow of cold air. (The crisper drawer will do just fine.) If you purchased your fluff balls from a farm, they might can be found in a ventilated bag of some kind, and you need to keep them in there, but a paper bag also works, offered you do not fill the bag more than halfway (let those infants breath).

When you’re ready to consume them, simply brush off any dirt with a mushroom brush (or a pastry brush) and cut off the little woody “foot.” If you merely need to clean them, wash them extremely rapidly under cold running water, and squeeze them gently to remove the excess. Tear them apart and let them dry on paper towels or a tidy hand towel prior to cooking.

How to eat ’em

Lion’s mane mushrooms are extremely soft and naturally rather damp, with a fun, bouncy texture that’s nearly meaty. Big mushrooms can be sliced into planks before pan frying in butter, or you can tear them into bite-sized morsels, toss them with oil, and roast till they are golden brown. Generally, cook them like you would any other mushroom (with butter), and eat them like you would any other mushroom (happily). (7 ).

Sources and dosing

Lion’s hair mushroom is offered as a supplement. In vitamin shops they are available in different ranges (e.g. Fermented Lion’s mane, powdered Lion’s hair mycelium, etc). Dosing is not fully known. One research study used 1g three times each day of powdered Lion’s hair fruiting bodies (Mori et al, 2009). Another pre-owned 3.2 g of powdered Lion’s hair fruiting bodies daily (Saitsu et al, 2019). Preclinical research studies utilized different extracts of Lion’s mane. (8 ).

Side Effects

When taken by mouth: Lion’s hair mushroom is potentially safe when used in a dose of 1 gram daily for 16 weeks. Adverse effects are moderate and may include stomach pain.

When applied to the skin: There isn’t enough trusted info to understand if lion’s hair mushroom is safe when applied to the skin or what the side effects might be. (9 ).

In Conclusion

The two crucial things to remember are that cancer treatments and nutrition are never the very same for everybody. Nutrition, that includes food and dietary supplements like Lion’s Hair Mushroom, is an efficient tool which can be managed by you, while facing cancer.

What food you consume and which supplements you take is a choice you make. Your choice must include factor to consider of the cancer gene anomalies, which cancer, ongoing treatments and supplements, any allergies, lifestyle info, weight, height and habits.

The nutrition preparation for cancer from addon is not based on web searches. It automates the choice producing you based upon molecular science carried out by our researchers and software engineers. Irrespective of whether you care to comprehend the underlying biochemical molecular pathways or not – for nutrition planning for cancer that understanding is needed.

Get going NOW with your nutrition preparation by addressing questions on the name of cancer, genetic mutations, ongoing treatments and supplements, any allergies, practices, way of life, age and gender. (10 ).

Recommendations

    1. Https://www.first-nature.com/fungi/hericium-erinaceus.php
    2. Https://www.rxlist.com/hericium_erinaceus/supplements.htm
    3. Https://www.mycomedica.eu/hericium.html
    4. Https://www.verywellmind.com/the-benefits-of-lions-mane-89474
    5. Https://www.verywellfit.com/lion-s-mane-nutrition-facts-and-health-benefits-5185393
    6. Https://psychcentral.com/health/lions-mane-mushroom-benefits#health-benefits
    7. Https://lifehacker.com/how-to-choose-store-and-eat-lions-mane-mushrooms-1845358782
    8. Https://www.alzdiscovery.org/uploads/cognitive_vitality_media/Lion’s-Mane-UPDATE.pdf
    9. Https://www.webmd.com/vitamins/ai/ingredientmono-1536/lions-mane-mushroom
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